Every millisecond of every day, you, everyone you know, every rock on the ground, every star in the sky... they're all aging. And podcasts are no exception. In fact, Tangents is hitting a milestone in its aging as we bring season 4 to a close with this episode! You can't hear the dull roar of time lurching ever onward if you're listening to a funny show, so come listen!

SciShow Tangents is on YouTube! Go to www.youtube.com/scishowtangents to check out this episode with the added bonus of seeing our faces!

Head to www.patreon.com/SciShowTangents to find out how you can help support SciShow Tangents, and see all the cool perks you’ll get in return, like bonus episodes and a monthly newsletter!

And go to https://store.dftba.com/collections/scishow-tangents to buy your very own, genuine SciShow Tangents sticker!

A big thank you to Patreon subscribers Garth Riley, Mike A, and Tom Mosner for helping to make the show possible!

Follow us on Twitter @SciShowTangents, where we’ll tweet out topics for upcoming episodes and you can ask the science couch questions!

While you're at it, check out the Tangents crew on Twitter: Ceri: @ceriley Sam: @im_sam_schultz Hank: @hankgreen

[Trivia Question]

Epigenetic clock of dog years vs. human years

https://www.smithsonianmag.com/smart-news/theres-new-better-formula-calculating-dog-years-180973575/

https://pubmed.ncbi.nlm.nih.gov/32619550/

[Fact Off]

Brown-Séquard and using testicle injections to reverse aging

https://archive.org/details/Brown-sequardC.-e.TheEffectProducedOnManBySubcutaneousInjectionsOfA

https://academic.oup.com/brain/article/140/5/1525/3760152

https://www.jci.org/articles/view/57089

Sperm aging/senescence in toads and other vertebrates

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050820

https://www.eurekalert.org/news-releases/683429

https://support.webb.uu.se/digitalAssets/52/a_52297-f_BeckyTREE.pdf

https://pubmed.ncbi.nlm.nih.gov/21332857/

[Ask the Science Couch]

Causing/reversing aging in mice through epigenetics (ICE - inducible changes to epigenome)

https://hms.harvard.edu/news/loss-epigenetic-information-can-drive-aging-restoration-can-reverse

https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7

https://www.news-medical.net/news/20230115/The-loss-of-epigenetic-information-accelerates-the-aging-process.aspx

https://newatlas.com/biology/epigenetic-reboot-reverse-aging-extend-lifespan

https://www.biorxiv.org/content/10.1101/2023.01.04.522507v1

https://www.nature.com/articles/s41586-020-2975-4

[Butt One More Thing]

C. elegans rapid senescence (kind of lactation)

https://www.eurekalert.org/news-releases/930463

https://www.nature.com/articles/s41467-021-25821-y

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